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Common complaints reported with varying frequency by patients treated with alprazolam include sedation, fatigue, ataxia, amnesia, slurred speech, poor concentration, hypersensitivity, and irritability. There are 3 case reports suggesting that valproate may be effective for the treatment of sedative-hypnotic withdrawal, but a double-blind, placebo-controlled study failed to replicate the results (Rickels et al., 1999). Rebound anxiety is common and is …